![]() Therefore, it is necessary to evaluate the existing upstream biological processes, to enable the selection of pilot-scale conditions for academic and industrial scientists to maximize the yield and quality of vaccine development and production. In particular, exploration at the laboratory-scale is urgently required for further development. The production of viral vaccines is inseparable from the development of upstream biological processes. ![]() In this context, the development and application of bioreactors can provide more efficient and cost-effective vaccine production to meet the global vaccine demand. ![]() Bioreactors are widely used in cell culture-based viral vaccine production, especially during the coronavirus disease 2019 (COVID-19) pandemic.
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